Actively Recruiting
Study of 129Xe Gas Exchange MRI to Understand Lung and Heart Function in Adults
Led by Bastiaan Driehuys · Updated on 2026-02-04
125
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
This NIH-sponsored study aims to characterize three biomarkers derived from 129Xe gas exchange MRI and understand how they change in response to interventions. The study focuses on markers derived from the interaction of 129Xe with pulmonary capillary red blood cells RBCs, specifically RBC transfer MRI, cardiogenic oscillations in 129Xe-RBC signal amplitude, and the 129Xe-RBC chemical shift. The study population includes healthy volunteers, patients scheduled to undergo transfusion or phlebotomy, patients with dyspnea, interstitial lung disease ILD, idiopathic pulmonary fibrosis IPF, non-specific interstitial pneumonias NSIP, chronic hypersensitivity pneumonitis cHP, sarcoid, chronic thromboembolic pulmonary hypertension CTEPH, and acute pulmonary embolism.
CONDITIONS
Brief Title
129Xe MRI Cardiopulmonary
Research Team
B
Bastiaan Driehuys, PhD
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