Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06958848

16F vs 24F Chest Drain After Minimally Invasive Lobectomy and/or Segmentectomy

Led by University Hospital, Basel, Switzerland · Updated on 2026-05-06

124

Participants Needed

1

Research Sites

121 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of the study is to evaluate postoperative pain in patients receiving a small-bore (16F) chest drain compared to those receiving the standard large-bore (24F) chest drain after minimally invasive pulmonary lobectomy and/or segmentectomy.

CONDITIONS

Official Title

16F vs 24F Chest Drain After Minimally Invasive Lobectomy and/or Segmentectomy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Signed informed consent by the patient (all sexes and genders)
  • Age 18 years or older with no upper age limit
  • American Society of Anaesthesiologists (ASA) physical status classification I to IV
  • Patients with resectable non-small cell lung cancer (NSCLC) suitable for minimally invasive surgery
  • Scheduled for minimally invasive anatomical lung resections under general anaesthesia including lobectomy, lobectomy with wedge resection, lobectomy with segmentectomy, segmentectomy with wedge resection, or bilobectomy
Not Eligible

You will not qualify if you...

  • Previous thoracic surgery on the same side within the last 3 months
  • Lung cancer complicated by pleural empyema
  • Chronic pain patients using opioids, gabapentin, or pregabalin
  • Current use of opiates or benzodiazepines
  • Congestive heart failure NYHA Class III or IV
  • Liver cirrhosis Child-Pugh Class B or C
  • Renal failure requiring dialysis or eGFR less than 30 mL/min/1.73 m2
  • Bleeding disorders including von Willebrand disease, hemophilia, or severe thrombocytopenia requiring platelet transfusion
  • Patients with neuralgia
  • Chest pain at surgery site greater than 10 mm on VAS while coughing without painkillers
  • Unhealed rib fractures on the side of surgery within the last 3 months
  • Open lung resections including pneumonectomy
  • Insertion of two or more chest tubes
  • Need for patient-controlled intravenous or epidural anaesthesia
  • Patients who are intubated or sedated and unable to complete pain surveys

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University Hospital Basel

Basel, Switzerland, 4031

Actively Recruiting

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Research Team

H

Helga Bachmann, MSc Clinical Research

CONTACT

M

Makhmudbek Mallaev, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

4

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