Actively Recruiting
18F-AraG PET/CT as a Non-Invasive Imaging Biomarker for Chemoradiation Treatment Response in Esophageal Cancer
Led by M.D. Anderson Cancer Center · Updated on 2026-05-06
60
Participants Needed
1
Research Sites
160 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To learn if 18F-FAraG PET scans can find tumors in participants with esophageal cancer and predict a participant's response to treatment.
CONDITIONS
Official Title
18F-AraG PET/CT as a Non-Invasive Imaging Biomarker for Chemoradiation Treatment Response in Esophageal Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants must be 18 years of age or older
- Participants with locally advanced esophageal cancer
- Participants with untreated documented carcinoma of the esophagus larger than 2 cm who will receive systemic therapy with radiation as primary treatment
- Ability to provide written informed consent
- Female participants of childbearing potential must have a negative pregnancy test within 1 week before the investigational PET/CT scan
- Female participants of childbearing potential must agree to use effective contraception or abstain from sexual activity during the study unless they are postmenopausal, have had hysterectomy or bilateral salpingo-oophorectomy, ovarian failure after pelvic radiation, or surgical sterilization
- Approved birth control methods include hormonal contraception, intrauterine device, tubal ligation, partner vasectomy, implantable or injectable contraceptives, and condoms plus spermicide
- Periodic abstinence, rhythm method, and withdrawal method are not acceptable birth control methods
You will not qualify if you...
- Body weight over 400 pounds or body habitus or disability preventing the imaging protocol
- Pregnant or lactating females
- History of allergic reaction to intravenous contrast
- Estimated glomerular filtration rate (eGFR) less than 40 within 1 month before receiving 18F-FAraG
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
MD Anderson Cancer Center
Houston, Texas, United States, 77030
Actively Recruiting
Research Team
S
Steven Lin, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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