Actively Recruiting
18F-DOPA II - PET Imaging Optimization
Led by University of Alberta · Updated on 2026-02-09
800
Participants Needed
1
Research Sites
358 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
A single centre non-randomized, non-blinded phase III prospective cohort study of 18F-DOPA PET/CT imaging in specific patient populations: 1. Pediatric patients (less than 18 years old) with congenital hyperinsulinism. 2. Pediatric patients (less than 18 years old) with neuroblastoma. 3. Pediatric (less than 18 years old) or Adult patients (18 or older) with known or clinically suspected neuroendocrine tumor. 4. Adult patients (18 or older) with a clinical suspicion of Parkinson's disease or Lewy body dementia. 5. Pediatric (less than 18 years old) or Adult patients (18 or older) with brain tumors. Image optimization (the primary study objective) and gallbladder activity pattern (the secondary objective) will be evaluated.
CONDITIONS
Official Title
18F-DOPA II - PET Imaging Optimization
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Pediatric patients (less than 18 years old) with congenital hyperinsulinism
- Pediatric patients (less than 18 years old) with neuroblastoma
- Pediatric (less than 18 years old) or adult patients (18 or older) with known or clinically suspected neuroendocrine tumor
- Adult patients (18 or older) with clinical suspicion of Parkinson's disease or Lewy body dementia
- Pediatric (less than 18 years old) or adult patients (18 or older) with brain tumors
You will not qualify if you...
- Unable to provide consent
- Weight over 225 kg (PET/CT scanner weight limit)
- Adult patients unable to lie flat for 20-30 minutes during the PET/CT scan
- Pediatric patients under 13 years old unable to lie flat for 20-30 minutes and for whom sedation is contraindicated
- Lack of intravenous access
- History of previous gallbladder removal (excluded from dynamic abdomen sub-study)
- Pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
WC Mackenzie Health Science Centre / University of Alberta Hospital
Edmonton, Alberta, Canada, T6G 2B7
Actively Recruiting
Research Team
J
Jonathan Abele, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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