Actively Recruiting

Phase 3
Age: 18Years +
All Genders
NCT06159335

18F-FLUC PET/MR in Patients With Brain Mets

Led by University of Wisconsin, Madison · Updated on 2026-02-03

30

Participants Needed

1

Research Sites

124 weeks

Total Duration

On this page

Sponsors

U

University of Wisconsin, Madison

Lead Sponsor

B

Blue Earth Diagnostics

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to use new imaging methods to help in finding out whether the imaging shows that there is a tumor in people with a brain metastasis. The main question it aims to answer is whether positron emission tomography (PET) and magnetic resonance imaging (MRI) find cancerous tissue better than other types of imagining. Participants will undergo a single PET/MRI scan, followed by a separate MRI scan with a tracer. Study participation will last about 3 hours.

CONDITIONS

Official Title

18F-FLUC PET/MR in Patients With Brain Mets

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Able and willing to provide informed consent
  • Diagnosed with brain metastasis with at least one visible contrast-enhancing lesion on brain MRI
  • Received radiation therapy within the last 2 years
  • Currently receiving or received systemic therapy such as immunotherapy, targeted therapy, or chemotherapy within the past 6 months
  • Recent standard-of-care MRI raises question of tumor recurrence versus treatment-related changes, or clinical concerns suggest progression versus treatment effects
  • Able to lie still for 30-60 minutes during imaging
  • Willing and able to undergo PET/MRI or PET/CT
  • If using mild oral anxiolytics for MRI, must have own prescription, provide consent before use, and have a driver to the visit
Not Eligible

You will not qualify if you...

  • Unable or unwilling to provide informed consent
  • Pregnant
  • Contraindications to or inability to undergo PET/MRI or PET/CT
  • Known allergy to 18F-Fluciclovine or any of its components

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Wisconsin

Madison, Wisconsin, United States, 53705

Actively Recruiting

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Research Team

R

Radiology Studies

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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