Actively Recruiting

Phase Not Applicable
MALE
NCT00588185

[18F]-Fluoro-2-Deoxy-D-Glucose and -[18F] Dihydro-Testosterone Pet Imaging in Patients With Progressive Prostate Cancer

Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-04-09

300

Participants Needed

7

Research Sites

1252 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study will use PET scans, which is a type of x-ray test that uses a radiotracer, to see whether these scans may be better able to find places in the body where your prostate cancer may have spread.

CONDITIONS

Official Title

[18F]-Fluoro-2-Deoxy-D-Glucose and -[18F] Dihydro-Testosterone Pet Imaging in Patients With Progressive Prostate Cancer

Who Can Participate

MALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with histologically confirmed prostate cancer.
  • Progressive disease shown by either new bone lesions on bone imaging, MRI or CT, or an increase in measurable soft tissue disease.
  • Biochemical progression defined by at least three rising PSA values one week apart or two measurements two or more weeks apart.
  • Visible lesions on CT, bone imaging, or MRI consistent with disease.
  • Ability to provide informed consent.
Not Eligible

You will not qualify if you...

  • Previous anaphylactic reaction to either FDHT or FDG.
  • Liver problems with bilirubin above 1.5 times the upper limit of normal, AST/ALT above 2.5 times normal, albumin below 2 g/dl, or GGT above 2.5 times normal if alkaline phosphatase is above 2.5 times normal.
  • Kidney problems with creatinine above 1.5 times normal or creatinine clearance below 60 mL/min.

AI-Screening

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Trial Site Locations

Total: 7 locations

1

Memorial Sloan Kettering Basking Ridge (Consent Only)

Basking Ridge, New Jersey, United States, 07920

Actively Recruiting

2

Memorial Sloan Kettering Monmouth (Consent only)

Middletown, New Jersey, United States, 07748

Actively Recruiting

3

Memorial Sloan Kettering Bergen (Consent Only)

Montvale, New Jersey, United States, 07645

Actively Recruiting

4

Memorial Sloan Kettering Commack (Consent only)

Commack, New York, United States, 11725

Actively Recruiting

5

Memorial Sloan Kettering Westchester (Consent only)

Harrison, New York, United States, 10604

Actively Recruiting

6

Memorial Sloan Kettering Cancer Center

New York, New York, United States, 10065

Actively Recruiting

7

Memorial Sloan Kettering Nassau (Consent Only)

Uniondale, New York, United States, 11553

Actively Recruiting

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Research Team

M

Michael Morris, M.D., PH.D.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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