Actively Recruiting
18F-FSPG PET in Imaging Patients With Liver Cancer Before Undergoing Surgery or Transplant
Led by M.D. Anderson Cancer Center · Updated on 2026-03-09
110
Participants Needed
1
Research Sites
275 weeks
Total Duration
On this page
Sponsors
M
M.D. Anderson Cancer Center
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This clinical trial studies fluorine F 18 L-glutamate derivative BAY94-9392 (18F-FSPG) positron emission tomography (PET) in imaging patients with liver cancer before undergoing surgery or transplant. Diagnostic procedures, such as 18F-FSPG PET, may help find and diagnose liver cancer and find out how far the disease has spread.
CONDITIONS
Official Title
18F-FSPG PET in Imaging Patients With Liver Cancer Before Undergoing Surgery or Transplant
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of hepatocellular carcinoma (HCC) meeting specific imaging or pathology criteria including LI-RADS features, AFP levels, or biopsy confirmation
- Diagnosis of benign liver tumor with suggestive imaging findings and prior MRI or CT within 8 weeks
- Diagnosis of malignant non-HCC liver tumor confirmed by biopsy or imaging and prior MRI or CT within 8 weeks
- Diagnosis of oligometastatic solid tumors in specified sites undergoing local therapy
- Completion of conventional imaging and staging including MRI or CT before investigational PET studies
- For HCC patients, eligibility for liver resection, orthotopic liver transplant (OLT), or Y90 radioembolization
You will not qualify if you...
- Under 18 years old
- Not a candidate for liver resection surgery, OLT, or Y90 radioembolization despite having HCC or cholangiocarcinoma
- Pregnant or breastfeeding without adequate birth control or negative pregnancy test prior to PET scans
- Poorly controlled diabetes mellitus with fasting blood glucose level over 200 mg/dL
- Known infiltrative variant of hepatocellular carcinoma (HCC)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
MD Anderson Cancer Center
Houston, Texas, United States, 77090
Actively Recruiting
Research Team
S
Simone S Krebs, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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