Actively Recruiting

Phase 2
Age: 19Years +
All Genders
NCT07314073

[18F]FES PET/CT for the Detection of Distant Metastasis in Low-grade ER-positive Stage III Breast Cancer

Led by Asan Medical Center · Updated on 2026-01-02

85

Participants Needed

1

Research Sites

209 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to evaluate the detection rate of distant metastases using \[18F\]FES PET/CT in patients with low-grade, ER-positive stage III breast cancer.

CONDITIONS

Official Title

[18F]FES PET/CT for the Detection of Distant Metastasis in Low-grade ER-positive Stage III Breast Cancer

Who Can Participate

Age: 19Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female patients aged 19 years or older
  • Newly diagnosed with invasive breast cancer within 90 days before screening, confirmed by histopathology
  • Histologically confirmed estrogen receptor-positive, histologic grade 1 or 2 primary breast cancer
  • Clinical stage IIIA to IIIC breast cancer according to AJCC 8th edition
  • Completed or scheduled chest CT, abdominal CT, and bone scintigraphy within 90 days before screening
  • Eastern Cooperative Oncology Group performance status score of 0 to 2
Not Eligible

You will not qualify if you...

  • Not having signed informed consent
  • Currently receiving systemic therapy for breast cancer (e.g., chemotherapy, hormonal therapy)
  • History of another invasive cancer within the past 2 years (except non-melanoma skin cancer)
  • Diagnosed with distant metastases on recent chest CT, abdominal CT, or bone scans within 90 days prior to screening
  • No biopsy or at least 6 months of follow-up imaging for suspicious lesions
  • Pregnant or breastfeeding women, except those postmenopausal, surgically sterile, or with a negative pregnancy test and using contraception
  • Serious or uncontrolled medical conditions such as heart failure, recent heart attack, severe lung, kidney, or liver disease
  • Relatives or students of the investigator or in dependent relationships
  • Unable to provide complete clinical trial data due to personal circumstances or other reasons

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Asan Medical Center

Seoul, South Korea

Actively Recruiting

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Research Team

S

Sangwon Han

CONTACT

J

Jaeeun Kim

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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