Using 2D Shear Wave Elastography of the Spleen to Detect Significant Portal Hypertension and High-risk Varices in Adults with Advanced Chronic Liver Disease

What this Trial Is About

Researchers are studying the use of spleen shear wave elastography SWE-SSM to help diagnose significant portal hypertension and high-risk esophageal varices in patients with advanced compensated chronic liver disease. The study aims to understand how well SWE-SSM can identify these conditions without affecting patient treatment or disease progression. It also explores how SWE-SSM relates to portal pressure and transient elastography measurements in some patients. During the ultrasound exams that patients normally undergo, spleen elastography will be added if the patient meets study criteria and consents. This additional test is non-invasive and does not change the standard ultrasound procedure or patient care. No treatments or experimental interventions will be given, as the study focuses on collecting clinical data through observation. Participants will have ultrasound exams including both spleen and liver elastography as part of their usual care pathway. Researchers will evaluate measurements related to portal hypertension and esophageal varices over a two-year period. The study monitors the natural course of the disease and gathers data without altering treatments or clinical management.

2D-shear Wave Spleen Elastography in Clinically Significant Portal Hypertension and High-risk Varices