Actively Recruiting

Age: 7Years - 15Years
All Genders
NCT06522607

3D Analysis of Palatal Morphology of Growing Patients Treated With Rapid Palatal Expander.

Led by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Updated on 2025-09-03

36

Participants Needed

1

Research Sites

128 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of the present study is to assess the changes of palatal morphology among growing patients with different vertical facial growth patterns treated with rapid palatal expander. Thirty-six patients referred to "Policlinico Agostino Gemelli" university hospital will be selected. The eligible criteria are posterior cross-bite, mixed dentition, skeletal Class I relationship and prepubertal stage of cervical vertebral maturation. The patients will be split into three groups according to facial divergency (hyper-, hypo-, normodivergent subjects). For each subject, digital dental casts will be recorded before and after treatment using an intraoral scanner. To evaluate two-dimensional maxillary arch changes, linear measurements will be done. To study comprehensively the palatal shape, a set of 240 landmark and semi-landmarks will be digitized on the palatal vault. Then, Geometric Morphometric Analysis (GMA) will be performed to compare morphological variations of the palate among different vertical facial growth pattern groups.

CONDITIONS

Official Title

3D Analysis of Palatal Morphology of Growing Patients Treated With Rapid Palatal Expander.

Who Can Participate

Age: 7Years - 15Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Caucasian origin
  • Mixed dentition stage
  • Angle class I or straight step or mesial step molar relationship in primary dentition
  • Skeletal class I (ANB angle between 0° and 5°)
  • Vertical dimension evaluated on lateral cephalograms: hyperdivergent if SN^GoGn > 37°, hypodivergent if SN^GoGn < 27°, normodivergent if between 27° and 37°
  • Cervical vertebral stage 1 or 2 (CVS methods 1-2)
  • Posterior cross-bite including deciduous or permanent teeth
  • Presence of good quality pre-treatment records including history, intraoral and extraoral photographs, oral scan, panoramic radiographs, and lateral cephalometric radiographs with reference ruler
  • Oral scan and photographs available 6 months after therapy begins
  • Signing the informed consent form
Not Eligible

You will not qualify if you...

  • Previous orthodontic treatment
  • Tooth agenesis or supernumerary teeth
  • Craniofacial abnormalities
  • Tooth impaction in the maxilla
  • Torus palatinus
  • History of dental trauma including avulsion and alveolar/jaw fracture
  • Refusal to sign consent form

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

UOC Clinica Odontoiatrica, Fondazione Poli..

Roma, Italy, 00168

Actively Recruiting

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Research Team

M

Massimo Cordaro

CONTACT

A

Angelica Guastamacchia

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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3D Analysis of Palatal Morphology of Growing Patients Treated With Rapid Palatal Expander. | DecenTrialz