Actively Recruiting
3D-MRE for Assessing Cirrhosis, Advanced Chronic Liver Disease and Portal Hypertension
Led by Shengjing Hospital · Updated on 2026-02-09
150
Participants Needed
1
Research Sites
224 weeks
Total Duration
On this page
Sponsors
S
Shengjing Hospital
Lead Sponsor
Z
Zhongda Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
How to construct a novel, non-invasive, accurate, and convenient method to achieve prediction of hepatic venous pressure gradient (HVPG) is an important general problem in the management of portal hypertension in cirrhosis or advanced chronic liver disease. We plan to investigate the ability of three demensional-magnetic resonance elastography (3D-MRE) to establish a risk stratification system and perform tailored management for portal hypertension in cirrhosis or advanced chronic liver disease.
CONDITIONS
Official Title
3D-MRE for Assessing Cirrhosis, Advanced Chronic Liver Disease and Portal Hypertension
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years or older
- Provided written informed consent
- Confirmed advanced chronic liver disease from any liver disease cause
- Clinically recommended for hepatic venous pressure gradient (HVPG) measurement with 3D-MRE done within one month before
You will not qualify if you...
- Presence of liver or other malignancies or large liver or spleen focal diseases affecting MRE
- Contraindications for MR or HVPG procedures
- Previous liver or spleen surgery affecting MRE results
- Treatment with nonselective beta-blockers between MRE and HVPG measurements
- Unreliable or invalid HVPG or MRE results
- Biliary obstruction or dilation seen on MR images
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Shengjing Hospital
Shenyang, Liaoning, China, 210000
Actively Recruiting
Research Team
Y
Yifei Huang, M.D.
CONTACT
Y
Yu Shi, Prof.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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