Higher-Resolution Magnetic Resonance Elastography in Meningiomas to Determine Intratumoral Consistency.
Joshua D Hughes, Nikoo Fattahi, J Van Gompel...
https://pubmed.ncbi.nlm.nih.gov/26197204Actively Recruiting
Phase Not Applicable
Age: 18Years - 80Years
All Genders
Healthy Volunteers
ID06955208
Evaluation of Meningioma Mechanical Properties and Histological Features Using Three-Dimensional Magnetic Resonance Elastography
Led by Shengjing Hospital · Updated on 2026-02-12
300
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This prospective single-center study aims to evaluate the feasibility and clinical utility of three-dimensional magnetic resonance elastography (3D MRE) in assessing tumor stiffness and adhesion in patients with meningioma undergoing surgical resection. By correlating preoperative MRE-derived stiffness and adhesion maps with intraoperative findings and histopathological features, the study seeks to determine whether MRE can serve as a noninvasive imaging biomarker for surgical planning, risk stratification, and prediction of tumor behavior.
CONDITIONS
Brief Title
3D MRE-Based Evaluation of Meningioma Mechanical Properties and Histological Features
Who Can Participate
Age: 18Years - 80Years
All Genders
Healthy Volunteers
Eligibility Criteria
You may qualify if you...
- All patients undergoing meningeoma resection surgery are eligible for inclusion in the study cohort.
You will not qualify if you...
- Patients with metallic implants or foreign bodies in their bodies (pacemakers, artificial metallic heart valves, metal joints, metal implants, and those who can not remove dentures, insulin pumps, or contraceptive rings)
- Pregnant women in the first trimester (within three months)
- Patients with severe claustrophobia or anxiety
- Patients with severe fever
- Patients who can not tolerate MRE
- Patients with vascular malformations and aneurysms.
- Patients who do not sign an informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Trial Site Locations
Total: 1 location
1
Shengjing Hospital
Shenyang, Liaoning, China, 110000
Actively Recruiting
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Research Team
Y
Yu Shi, MD
W
Wen Cheng, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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Published Research Related To This Trial
A new method for quantification and 3D visualization of brain tumor adhesion using slip interface imaging in patients with meningiomas.
Ziying Yin, Xin Lu, Salomon Cohen Cohen...
https://pubmed.ncbi.nlm.nih.gov/33852045Slip interface imaging based on MR-elastography preoperatively predicts meningioma-brain adhesion.
Ziying Yin, Joshua D Hughes, Joshua D Trzasko...
https://pubmed.ncbi.nlm.nih.gov/28194925