Evaluation of Meningioma Mechanical Properties and Histological Features Using Three-Dimensional Magnetic Resonance Elastography

Led by Shengjing Hospital · Updated on 2026-02-12

300

Participants Needed

Research Sites

52 weeks

Total Duration

AI-Summary

What this Trial Is About

This prospective single-center study aims to evaluate the feasibility and clinical utility of three-dimensional magnetic resonance elastography (3D MRE) in assessing tumor stiffness and adhesion in patients with meningioma undergoing surgical resection. By correlating preoperative MRE-derived stiffness and adhesion maps with intraoperative findings and histopathological features, the study seeks to determine whether MRE can serve as a noninvasive imaging biomarker for surgical planning, risk stratification, and prediction of tumor behavior.

CONDITIONS

Brief Title

3D MRE-Based Evaluation of Meningioma Mechanical Properties and Histological Features

Who Can Participate

Age: 18Years - 80Years

All Genders

Healthy Volunteers

Eligibility Criteria

Inclusion Criteria:

All patients undergoing meningeoma resection surgery are eligible for inclusion in the study cohort.

Exclusion Criteria:

Patients with metallic implants or foreign bodies in their bodies (pacemakers, artificial metallic heart valves, metal joints, metal implants, and those who can not remove dentures, insulin pumps, or contraceptive rings)
Pregnant women in the first trimester (within three months)
Patients with severe claustrophobia or anxiety
Patients with severe fever
Patients who can not tolerate MRE
Patients with vascular malformations and aneurysms.
Patients who do not sign an informed consent

Research Team

Yu Shi, MD

Wen Cheng, MD

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here