Actively Recruiting
3D OPTIMIZED WMN MPRAGE Increased Detection of Focal Spinal Cord Lesion in Multiple Sclerosis (WHINUME)
Led by University Hospital, Bordeaux · Updated on 2025-06-29
60
Participants Needed
1
Research Sites
143 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of this study is to compare the 3D OPTIMIZED MPRAGE WMN sequence to "conventional sequences" used in spinal cord analysis. The patients will be explored at the cervical level with the conventional 2D sagittal T2 FSE, 2D sagittal STIR, 2D sagittal PSIR, 3D T1 MPRAGE sequences, and the sequence of interest 3D sagittal OPTIMIZED WMN MPRAGE and 3D axial OPTIMIZED WMN MPRAGE. At the thoracic level, with the conventional 2D sagittal T2 FSE, 2D sagittal STIR, 3D T1 MPRAGE sequences and the sequence of interest 3D sagittal OPTIMIZED WMN MPRAGE.
CONDITIONS
Official Title
3D OPTIMIZED WMN MPRAGE Increased Detection of Focal Spinal Cord Lesion in Multiple Sclerosis (WHINUME)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients older than 18 years old
- Diagnosis of Clinically Isolated Syndrome (CIS) or Relapsing-Remitting Multiple Sclerosis (RRMS)
- Medullary symptomatology lasting less than 6 months
- Presence or absence of an objective lesion on a subsequent MRI scan
- Signed informed consent form
You will not qualify if you...
- Pregnant or potentially pregnant women
- Breastfeeding women
- Contraindications to MRI
- Diagnoses other than multiple sclerosis such as Neuro-myelitis spectrum disease or Progressive Multiple Sclerosis
- History of spinal cord or lumbar spine surgery
- Patients under legal protection
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
CHU de Bordeaux
Bordeaux, France
Actively Recruiting
Research Team
V
Vincent Dousset, MD, PhD
CONTACT
A
Amaury Ravache, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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