Actively Recruiting

FEMALE
Healthy Volunteers
ID06755047

3D Ultrasound Placental Volume and Vascular Indices Versus 2D Parameters for Diagnosis of Placenta Accreta Spectrum

Led by Assiut University · Updated on 2025-01-01

38

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Placenta accreta spectrum disorders (PASD) include abnormal implantation of the placenta into the uterine wall, such as placenta accreta, increta, and percreta. This condition is a significant obstetric concern, and current antenatal diagnostic methods do not provide complete certainty in diagnosis. This study aims to compare two common ultrasound methods, 3D ultrasound and 2D ultrasound with color Doppler, to assess their effectiveness in diagnosing placenta accreta spectrum. The study evaluates 3D ultrasound using placental volume measurements and vascular indices including vascularization index, flow index, and vascularization flow index. The 2D ultrasound assessment includes examining placental invasion criteria such as lacunar vascular flow, abnormal utero-placental interface, myometrial thinning, absence of retroplacental myometrium, interruptions at the utero-vesical interface, and lower uterine segment hypervascularity. These two diagnostic approaches are observed and compared during the study period. Participants will be pregnant women diagnosed with placenta previa and will undergo ultrasound examinations using both 3D and 2D methods. The primary outcome measure is the vascular index assessed at 1 month. Secondary outcomes include evaluation of 2D ultrasound parameters at the same time point. This observational study involves ultrasound imaging to monitor placental characteristics and blood flow, aiming to improve antenatal diagnosis of placenta accreta spectrum disorders.

CONDITIONS

Brief Title

3D Placental Volume in Placenta Accreta

Who Can Participate

FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Pregnant women with placenta previa
Not Eligible

You will not qualify if you...

  • Congenital anomalies of the placenta
  • Placental separation
  • Uterine anomalies

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Up to 1 month

Participants undergo 3D and 2D ultrasound examinations to assess placental volume and vascular indices for diagnosis of placenta accreta spectrum.

1 to 2 ultrasound visits

Long-term Monitoring

Duration - Up to delivery

Participants are monitored for pregnancy outcomes related to placenta accreta spectrum after diagnostic assessments.

Visits according to routine prenatal care

Trial Site Locations

Total: 1 location

1

Women's Health Hospital

Asyut, Egypt

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Research Team

M

Mohamed Fekry, PhD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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