Actively Recruiting
3D Printed Custom Applicators for HDR BT (DISCO)
Led by Royal North Shore Hospital · Updated on 2026-02-06
10
Participants Needed
1
Research Sites
249 weeks
Total Duration
On this page
Sponsors
R
Royal North Shore Hospital
Lead Sponsor
N
Northern Sydney and Central Coast Area Health Service
Collaborating Sponsor
AI-Summary
What this Trial Is About
Intracavitary brachytherapy for gynaecological cancer currently use cylinder-type applicators or custom wax moulds to place a radioactive source in close proximity to the treatment area and provide highly conformal dose distributions. This study is a Phase IIa non-randomised interventional pilot trial that will investigate the feasibility of successfully treating patients with 3D-printed custom applicators.
CONDITIONS
Official Title
3D Printed Custom Applicators for HDR BT (DISCO)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Able to give informed consent
- Patients indicated for intracavitary brachytherapy
- FIGO stage I-IVA
- ECOG performance status 0-2
- Primary endometrial cancer, primary vaginal cancer, primary vulva cancer, or recurrent gynaecological cancer
You will not qualify if you...
- Pregnancy
- Patients contraindicated for brachytherapy
- History of inflammatory bowel disease, adhesions, or bowel obstruction
- Renal transplant or horseshoe kidney
- Significant lymphovascular space invasion (LVSI) or pelvic sidewall invasion
- Patients requiring interstitial brachytherapy implants
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Royal North Shore Hospital
St Leonards, New South Wales, Australia, 2067
Actively Recruiting
Research Team
M
Marita Morgia, MD
CONTACT
J
Jeremy Booth, PhD QMP
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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