Actively Recruiting

Age: 18Years - 80Years
All Genders
NCT07436598

3D Virtual Resection for Predicting Lung Function in VATS

Led by National Taiwan University Hospital · Updated on 2026-05-13

60

Participants Needed

1

Research Sites

64 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to validate a novel preoperative assessment strategy using three-dimensional (3-D) computed tomography (CT) reconstruction and virtual resection simulation. The goal is to accurately predict postoperative pulmonary function in patients with non-small cell lung cancer (NSCLC) undergoing Video-Assisted Thoracoscopic Surgery (VATS) anatomical resection. Accurate prediction of postoperative lung function is crucial for patient safety. Traditional methods, such as segment counting, often lack precision because they assume all lung segments contribute equally to function, ignoring variations caused by tumors or emphysema. This study utilizes 3-D "virtual resection" to quantify the "Planned Resected Ventilated Lung Volume Fraction" (pRVLVF) before surgery. The study will recruit 60 participants divided into two groups: those undergoing lobectomy (n=30) and those undergoing segmentectomy (n=30). Participants will undergo standard thin-slice CT scans and pulmonary function tests (PFT) before surgery. Postoperatively, lung function and recovery will be tracked at 3, 6, and 12 months to develop a dynamic prediction model and evaluate the compensatory capacity of the residual lung.

CONDITIONS

Official Title

3D Virtual Resection for Predicting Lung Function in VATS

Who Can Participate

Age: 18Years - 80Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Scheduled for video-assisted thoracoscopic (VATS) lobectomy or segmentectomy at National Taiwan University Hospital or NTU Cancer Center
  • Age between 18 and 80 years
  • Signed informed consent agreeing to provide imaging data for 3D modeling
Not Eligible

You will not qualify if you...

  • Age younger than 18 or older than 80 years
  • Not scheduled for VATS lobectomy or segmentectomy
  • Diagnosed with Chronic Obstructive Pulmonary Disease (COPD)
  • Unable or unwilling to sign informed consent
  • Vulnerable populations

AI-Screening

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Trial Site Locations

Total: 1 location

1

National Taiwan University Cancer Center

Taipei, Taiwan

Actively Recruiting

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Research Team

C

Chih-Hsiang Chang, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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