Actively Recruiting

Phase Not Applicable
Age: 18Years +
FEMALE
NCT04705467

3DUS Imaging of Needles in Gynecological Brachytherapy

Led by Western University, Canada · Updated on 2025-04-13

35

Participants Needed

1

Research Sites

189 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Brachytherapy treatment in gynecological cancers is an essential component to delivering adequate doses of radiation to a tumour while sparing normal tissue. Interstitial or intra-cavitary brachytherapy are often needed in advanced or recurrent disease, in cases where intrauterine brachytherapy may not deliver the optimal outcome. Interstitial or intra-cavitary brachytherapy are based on a defined template-and-needle system, and the procedure relies on clinical examination and pre-treatment imaging to guide needle insertion. There is currently no standard image-guided process to help direct needles in the pelvis. We propose using 3D ultrasound to provide real-time imaging for the brachytherapy procedure, which will aid in avoiding needle insertion into pelvic organs and result in optimal dose coverage to the tumour.

CONDITIONS

Official Title

3DUS Imaging of Needles in Gynecological Brachytherapy

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Female, age 18 years or older
  • Diagnosed with locally advanced or recurrent gynecological malignancies
  • Offered interstitial or ring and tandem brachytherapy treatment
  • Includes patients with primary or recurrent vaginal, endometrial, or cervical cancers
  • Cancer histologies typically adenocarcinomas or squamous cell carcinomas
Not Eligible

You will not qualify if you...

  • Patients not offered interstitial brachytherapy as a treatment option

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

London Regional Cancer Program, Victoria Hospital

London, Ontario, Canada, N6A 5W9

Actively Recruiting

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Research Team

D

David D'Souza, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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