Actively Recruiting
45th Multicenter Airway Research Collaboration
Led by Massachusetts General Hospital · Updated on 2026-04-17
1860
Participants Needed
1
Research Sites
81 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The study is a randomized controlled trial on the effect of emergency department initiation of Airsupra on acute asthma "recurrence" at 3 months and other related outcomes (acute asthma relapse, asthma control).
CONDITIONS
Official Title
45th Multicenter Airway Research Collaboration
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Acute asthma diagnosis
- Age between 18.0 and 54.9 years
- English and/or Spanish speaking
- Decision by ED doctor to discharge patient home with a short course of systemic corticosteroids
- Willingness to use Airsupra as rescue inhaler for next 3 months (intervention group only)
- Ability to properly use a metered-dose inhaler
- Provided informed consent before any study procedures
You will not qualify if you...
- Involvement in planning or conducting this study
- Previous enrollment in this study
- Prior diagnosis of COPD, chronic bronchitis, or emphysema
- Use of systemic corticosteroids in past 2 weeks
- Participation in another investigational study within the past 4 weeks or 3 months after enrollment
- Concurrent pneumonia
- Clinically significant heart disease or cancer
- Known allergy to Airsupra, albuterol sulfate, budesonide, or any product ingredients
- For women: currently pregnant or breastfeeding
- Sexually active women of childbearing age not using adequate contraception recently or planning to use it
- Lack of working cell phone and email
- Expected unavailability for follow-up by text or phone at 3, 6, and 12 weeks
- Unable to provide an alternate contact with working phone and email
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
MetroHealth
Cleveland, Ohio, United States, 44109
Actively Recruiting
Research Team
C
Carlos A Camargo, MD, DrPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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