Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT05873777

68Ga-FAPI-LM3 PET/CT Imaging in Patients With FAP/SSTR2 Positive Disease and Compared With 18F-FDG

Led by The First Affiliated Hospital of Xiamen University · Updated on 2025-08-08

30

Participants Needed

1

Research Sites

142 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

As a new dual receptor (SSTR2 and FAP) targeting PET radiotracer, 68Ga-FAPI-LM3 is promising as an excellent imaging agent applicable to SSTR2 positive diseases. In this research, we investigate the safety, biodistribution and radiation dosimetry of 68Ga-FAPI-LM3 in healthy volunteers. Moreover, we evaluate the potential usefulness of 68Ga-FAPI-LM3 positron emission tomography/computed tomography (PET/CT) for the diagnosis of lesions in SSTR2 positive diseases, and compared with 18F-FDG PET/CT.

CONDITIONS

Official Title

68Ga-FAPI-LM3 PET/CT Imaging in Patients With FAP/SSTR2 Positive Disease and Compared With 18F-FDG

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients aged 18 years or older
  • Patients with suspected, newly diagnosed, or previously diagnosed malignant disease expressing FAP or SSTR2 (confirmed by MRI, CT, pathology, etc.)
  • Patients scheduled for both 18F-FDG and 68Ga-FAPI-LM3 PET/CT scans
  • Patients able to provide informed consent and assent according to ethics guidelines
Not Eligible

You will not qualify if you...

  • Patients with non-malignant disease
  • Patients who are pregnant
  • Patients or legal representatives unwilling or unable to provide written informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The First Affiliated Hospital of Xiamen University

Xiamen, Fujian, China, 0086-361000

Actively Recruiting

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Research Team

L

Long Sun, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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