Actively Recruiting
68Ga-FAPI PET/CT in Malignant Tumors
Led by Zhongnan Hospital · Updated on 2025-06-05
500
Participants Needed
1
Research Sites
253 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Fibroblast-activation protein (FAP) is a type Ⅱ transmembrane serine protease and is overexpressed in cancer-associated fibroblasts (CAFs). CAFs are the predominant component in the stroma of epithelial neoplasms. FAP can be detected in various of malignant neoplasms and is associated to tumor cell migration, invasion, and angiogenesis. Recently, a novel molecular probe, gallium 68-labelled FAP inhibitor (68Ga-FAPI), has been developed and used for visualization of tumor stroma by targeting FAP. Recent studies show favorable diagnosis efficiency in a variety of tumors, especially in gastrointestinal cancer, but the previous studies were all small-sample data or case reports. Therefore, further large-size research is necessary to confirm the advantages of 68Ga-FAPI in various of malignant tumors.
CONDITIONS
Official Title
68Ga-FAPI PET/CT in Malignant Tumors
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Volunteering to participate in clinical trial and signing an informed consent form
- Patients with suspected or confirmed malignant tumor
You will not qualify if you...
- Female patients planning to become pregnant within 6 months
- Pregnant and lactating women
- Patients allergic to multiple drugs including the test drug
- Patients who have participated in other clinical trials in the past one month
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Zhongnan Hospital of Wuhan University
Wuhan, Hubei, China, 430071
Actively Recruiting
Research Team
Y
Yong He, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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