Actively Recruiting

Phase 2
Age: 18Years +
All Genders
NCT06613269

68Ga-NY104 PET/CT Guided Radiation Therapy in CcRCC.

Led by Peking Union Medical College Hospital · Updated on 2024-09-27

40

Participants Needed

1

Research Sites

231 weeks

Total Duration

On this page

Sponsors

P

Peking Union Medical College Hospital

Lead Sponsor

P

Peking University First Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

Radiation therapy (RT) is an effective treatment for patients with advanced-stage clear cell renal cell carcinoma (ccRCC). Current evidence has shown promising outcomes combining radiation therapy and standard systemic therapy in patients with metastatic/recurrent ccRCC. CAIX is a highly sensitive and specific biomarker expressed on ccRCC and in previous studies the investigators have shown excellent diagnostic efficacy of 68Ga-NY104, a CAIX-targeted PET tracer, in patients with metastatic ccRCC. In this study, the investigators aim to investigate the effect of 68Ga-NY104, and 18F-FDG PET/CT guided RT combining standard systemic therapy in patients with metastatic ccRCC.

CONDITIONS

Official Title

68Ga-NY104 PET/CT Guided Radiation Therapy in CcRCC.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 63 18 years old
  • Histologically or cytologically confirmed clear cell renal cell carcinoma
  • Eligible for radiation therapy with no more than 10 lesions in total
  • Expected survival of more than 3 months
  • Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1
  • Sufficient organ function
  • Provided written informed consent
Not Eligible

You will not qualify if you...

  • Presence of brain metastasis or carcinomatous meningitis
  • Other malignant tumors not controlled within the past 5 years, except for non-metastatic low-risk prostate cancer
  • Pregnant or breastfeeding
  • Active infection

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Peking University First Hospital

Beijing, Beijing Municipality, China, 100034

Actively Recruiting

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Research Team

X

Xianshu Gao, MD

CONTACT

M

Mingwei Ma, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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68Ga-NY104 PET/CT Guided Radiation Therapy in CcRCC. | DecenTrialz