Actively Recruiting

Phase 1
Age: 18Years - 89Years
All Genders
NCT07020806

[68Ga]Ga DOTA-5G as a Diagnostic Imaging Agent for Metastatic/Advanced Invasive Lobular Breast Cancer (LBC)

Led by University of California, Davis · Updated on 2026-03-23

30

Participants Needed

1

Research Sites

80 weeks

Total Duration

On this page

Sponsors

U

University of California, Davis

Lead Sponsor

D

Dr. Helen K Chew, University of California Davis

Collaborating Sponsor

AI-Summary

What this Trial Is About

This is a prospective study using \[68Ga\]Ga DOTA-5G PET/CT imaging in patients diagnosed with metastatic/advanced invasive lobular breast cancer (LBC).

CONDITIONS

Official Title

[68Ga]Ga DOTA-5G as a Diagnostic Imaging Agent for Metastatic/Advanced Invasive Lobular Breast Cancer (LBC)

Who Can Participate

Age: 18Years - 89Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Ability to understand and willingness to sign a written informed consent document
  • Men and women age 63; 18 years
  • Confirmed presence of metastatic/advanced invasive lobular breast cancer with measurable disease per RECIST (version 1.1) or PERCIST
  • Availability of archival tumor tissue
  • Eastern Cooperative Oncology Group Performance Status 64; 2
  • Hematologic parameters: Absolute neutrophil count (ANC) 63; 1000 cells/mm3, Platelet count 63; 100,000/mm3, Hemoglobin 63; 8 g/dL
  • Blood chemistry levels: AST, ALT, alkaline phosphatase 64; 5 times upper limit of normal, Total bilirubin 64; 2 times upper limit of normal, eGFR �3E; 60 mL/min/1.73m2
  • Anticipated life expectancy 63; 3 months
  • Able to remain motionless for up to 30-60 minutes per scan
Not Eligible

You will not qualify if you...

  • Pregnant and lactating women
  • Prisoners
  • Concurrent malignancy of a different histology that could confound imaging interpretation
  • Patients who cannot undergo PET/CT scanning because of weight limits (>350 lbs)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Trial Site Locations

Total: 1 location

1

University of California Davis

Sacramento, California, United States, 95817

Actively Recruiting

Loading map...

Research Team

J

Julie Sutcliffe, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here