Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06275477

68Gallium-FAPI46 PET/CT Imaging in Chronic Inflammatory and Fibrotic Diseases

Led by University Hospital, Brest · Updated on 2026-03-04

390

Participants Needed

1

Research Sites

131 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This single-center pilot study is designed to explore the preliminary utility of the \[68Ga\] Ga-FAPI imaging agent in positron emission tomography (PET) combined with computed tomography (CT) for a range of chronic inflammatory and fibrosing diseases. The study focuses on the potential of \[68Ga\] Ga-FAPI, a novel radiotracer targeting Fibroblast Activation Protein (FAP), to improve diagnostic accuracy in various medical conditions. Thirteen distinct clinical situations have been selected for this investigation, including rheumatoid arthritis, liver fibrosis, and systemic lupus, among others. This approach aims to ascertain the value of further clinical development in each area and refine the use of this imaging modality in routine care for both initial evaluation and ongoing monitoring of these diseases.

CONDITIONS

Official Title

68Gallium-FAPI46 PET/CT Imaging in Chronic Inflammatory and Fibrotic Diseases

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient aged 18 or over
  • Diagnosed with one of the study's specified diseases
  • Meets confirmed classification criteria for their disease
  • Matches the defined clinical situation for their condition
  • Negative pregnancy test if woman of childbearing age
  • Affiliated with or covered by social security
  • Provided informed consent personally or via a representative
Not Eligible

You will not qualify if you...

  • Unable to provide informed consent
  • Adults declared incapacitated
  • Pregnant or breastfeeding women
  • Individuals refusing to participate in research
  • Known active cancer
  • Women of childbearing potential not using appropriate contraception

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Chu Brest

Brest, France, 29200

Actively Recruiting

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Research Team

P

Pierre-Yves LE ROUX, PHD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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