Actively Recruiting
7T Anatomo-functional Characterization of Structures in the Action Observation Network
Led by IRCCS Fondazione Stella Maris · Updated on 2025-02-13
40
Participants Needed
2
Research Sites
35 weeks
Total Duration
On this page
Sponsors
I
IRCCS Fondazione Stella Maris
Lead Sponsor
U
University of Parma
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this study is to explore the anatomical-functional characteristics of the AON circuit (with particular interest for subcortical areas and the cerebellum), and the cortico-subcortical connectivity of the nodes of the AON circuit, using an ultra-high field (7T), high spatial resolution Magnetic Resonance Imaging protocol. The main questions it aims to answer are: * Can we demonstrate the involvement of subcortical areas and cerebellum in the AON circuit in each single-subject? * Can we obtain similar results in a small group of patients with Cerebral Palsy (CP), in order to demonstrate the feasibility of this approach for the study of the mechanisms of AON reorganization, after early brain damage? * Are different patterns of functional activation correlated to different clinical characteristics of CP patients? Participants will perform a 7 Tesla MRI scan, with a functional and anatomical dedicated protocol and will have a comprehensive clinical assessment before the MRI exam.
CONDITIONS
Official Title
7T Anatomo-functional Characterization of Structures in the Action Observation Network
Who Can Participate
Eligibility Criteria
You may qualify if you...
- For CP patients: documented brain injury from pre-, peri-, or post-natal period
- Intellectual development within normal or mild deficit range to ensure cooperation
- Understanding of the Italian language
- For healthy controls: no known neurological or psychiatric disorders
- Understanding of the Italian language
You will not qualify if you...
- Contraindications to undergoing 7T fMRI exam
- Neuropsychiatric conditions preventing cooperation with the 7T fMRI study
- Lack of capacity to understand and consent
- Pregnancy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Fondazione IMAGO7
Calambrone, PISA, Italy, 56018
Active, Not Recruiting
2
IRCCS Fondazione Stella Maris
Calambrone, Pisa, Italy, 56018
Actively Recruiting
Research Team
L
Laura Biagi, PhD
CONTACT
G
Giuseppina Sgandurra, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here