Actively Recruiting

Phase 2
Phase 3
Age: 18Years +
All Genders
NCT05891769

99mTc Sestamibi SPECT/CT vs 18F Fluorocholine PET/CT

Led by Andrei Iagaru · Updated on 2025-09-10

100

Participants Needed

1

Research Sites

196 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study proposes the use of a well-established PET isotope, Fluorine-18 (18F), bound to Choline, for a prospective single-center, single-arm study for participants with suspected parathyroid adenoma and negative or equivocal standard of care 99mTc Sestamibi SPECT/CT

CONDITIONS

Official Title

99mTc Sestamibi SPECT/CT vs 18F Fluorocholine PET/CT

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Suspected parathyroid adenoma with elevated serum calcium and inappropriately normal or high parathyroid hormone levels
  • Negative or equivocal 99mTc Sestamibi SPECT/CT scan
  • Able to provide written consent
  • Total bilirubin less than or equal to 1.5 times the upper limit of normal
  • Alanine aminotransferase (ALT) or aspartate aminotransferase (AST) less than or equal to 5 times the upper limit of normal
  • Karnofsky performance status greater than 50 or equivalent ECOG/WHO score
  • Women must not be pregnant according to radiology policy
Not Eligible

You will not qualify if you...

  • Younger than 18 years at the time of radiotracer administration
  • Creatinine clearance less than 60 mL/min or serum creatinine greater than 1.5 times the upper limit of normal
  • QTcF interval greater than 470 msec on ECG or congenital long QT syndrome

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Stanford Hospital and Clinics

Stanford, California, United States, 94305

Actively Recruiting

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Research Team

A

Andrea Otte, DPT

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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