Status:

UNKNOWN

Herpetic Eye Disease Study (HEDS) I

Lead Sponsor:

National Eye Institute (NEI)

Conditions:

Keratitis, Herpetic

Ocular Herpes Simplex

Eligibility:

All Genders

12+ years

Phase:

PHASE3

Brief Summary

To evaluate the efficacy of topical corticosteroids in treating herpes simplex stromal keratitis in conjunction with topical trifluridine. To evaluate the efficacy of oral acyclovir in treating herpe...

Detailed Description

Herpes simplex keratitis is a leading cause of corneal opacification in the United States, other industrialized countries, and developing nations throughout the world. An estimated 450,000 people in t...

Eligibility Criteria

Eligibility criteria common to the three protocols included age 12 years or older, no active HSV epithelial keratitis, no prior keratoplasty of the involved eye, and not pregnant. Protocol-specific criteria are noted in the description above.

Key Trial Info

Start Date :

May 1 1989

Trial Type :

INTERVENTIONAL

End Date :

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00000138

Start Date

May 1 1989

Last Update

September 17 2009

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