Status:

UNKNOWN

Herpetic Eye Disease Study (HEDS) I

Lead Sponsor:

National Eye Institute (NEI)

Conditions:

Keratitis, Herpetic

Ocular Herpes Simplex

Eligibility:

All Genders

12+ years

Phase:

PHASE3

Brief Summary

To evaluate the efficacy of topical corticosteroids in treating herpes simplex stromal keratitis in conjunction with topical trifluridine. To evaluate the efficacy of oral acyclovir in treating herpe...

Detailed Description

Herpes simplex keratitis is a leading cause of corneal opacification in the United States, other industrialized countries, and developing nations throughout the world. An estimated 450,000 people in t...

Eligibility Criteria

Inclusion

  • Eligibility criteria common to the three protocols included age 12 years or older, no active HSV epithelial keratitis, no prior keratoplasty of the involved eye, and not pregnant. Protocol-specific criteria are noted in the description above.

Exclusion

    Key Trial Info

    Start Date :

    May 1 1989

    Trial Type :

    INTERVENTIONAL

    End Date :

    Estimated Enrollment :

    Patients enrolled

    Trial Details

    Trial ID

    NCT00000138

    Start Date

    May 1 1989

    Last Update

    September 17 2009

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    Herpetic Eye Disease Study (HEDS) I | DecenTrialz