Status:
COMPLETED
Herpetic Eye Disease Study (HEDS) II
Lead Sponsor:
National Eye Institute (NEI)
Conditions:
Keratitis, Herpetic
Ocular Herpes Simplex
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
To determine whether early treatment (with oral acyclovir) of herpes simplex virus (HSV) ulcerations of the corneal epithelium prevents progression to the blinding complications of stromal keratitis a...
Detailed Description
Infection of the eye by herpes simplex virus (HSV) is a leading cause of corneal blindness in the United States and other countries. The infection can lead to corneal scarring and neovascularization, ...
Eligibility Criteria
Protocol-specific criteria are noted in the description above.
Key Trial Info
Start Date :
October 1 1992
Trial Type :
INTERVENTIONAL
End Date :
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00000139
Start Date
October 1 1992
Last Update
March 24 2010
Active Locations (8)
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1
Francis I. Proctor Foundation, University of California, San Francisco
San Francisco, California, United States
2
Emory Eye Center
Atlanta, Georgia, United States
3
Eye Center, University of Illinois, Chicago
Chicago, Illinois, United States
4
Louisiana State University Eye Center
New Orleans, Louisiana, United States