Status:
COMPLETED
Effects of Carvedilol on Cocaine Use in Humans - 11
Lead Sponsor:
National Institute on Drug Abuse (NIDA)
Collaborating Sponsors:
University of Minnesota
Conditions:
Cocaine-Related Disorders
Eligibility:
All Genders
20-55 years
Phase:
PHASE2
Brief Summary
The purpose of this study is to examine carvedilol effects in response to cocaine.
Detailed Description
The purpose of this study was to determine whether carvedilol, and alpha and beta adrenergic blocker, would inhibit the priming effect of cocaine in a laboratory model. A total of 12 subjects were enr...
Eligibility Criteria
Inclusion Criteria:
Male/Female between 20 and 55. History of smoked or intravenous cocaine use on the average of at least once a week over a 6 month period. current history of good health and normal EKG. Not pregnant as determined by pregnancy screening nor breast feeding, using acceptable birth control methods (e.g. birth control pills diaphragm, condoms plus foam)
Exclusion Criteria:
Current problems with major psychiatric illnesses including bipolar disorder, schizophrenia, or anxiety disorders. History of major medical illnesses including asthma and chronic obstructive pulmonary disease. Currently on a drug related parole or probation. Treated for chemical dependency withing the past 6 months.
Key Trial Info
Start Date :
September 1 1998
Trial Type :
INTERVENTIONAL
End Date :
December 1 2001
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00000294
Start Date
September 1 1998
End Date
December 1 2001
Last Update
January 12 2017
Active Locations (1)
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1
University of Minnesota
Minneapolis, Minnesota, United States, 55455