Status:
UNKNOWN
Effects of Stimulant Dependence on Human Striatal Dopamine System - 15
Lead Sponsor:
National Institute on Drug Abuse (NIDA)
Conditions:
Amphetamine-Related Disorders
Tobacco Use Disorder
Eligibility:
All Genders
21-50 years
Phase:
PHASE1
Brief Summary
The purpose of this study is to determine whether DAT availability, assessed by WIN binding, in the striatum is altered in cocaine or methamphetamine dependence. To determine whether DA synthesis capa...
Detailed Description
4-5 Day inpatient study. Participant will have scanned pictures (MRI \& PET scans) taken of their brain after being injected with a small amount of WIN, a radioactive substance. Participants give dail...
Eligibility Criteria
Inclusion Criteria:
M/F, ages 21-50. Meet DSM-IV criteria for methamphetamine and nicotine dependence. Agree to conditions of the study and sign informed consent.
Exclusion Criteria:
Psychiatric disorder that requires medication therapy. History of seizures. Pregnant and/or nursing women. Dependence on ETOH or benzodiazepines or other sedative/hypnotics. Acute hepatitis. Other medical conditions that deem participation to be unsafe.
Key Trial Info
Start Date :
March 1 1999
Trial Type :
INTERVENTIONAL
End Date :
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00000350
Start Date
March 1 1999
Last Update
January 11 2017
Active Locations (1)
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1
Friends Research Institute
Los Angeles, California, United States, 90025