Status:

COMPLETED

Effects of Strength Training on Knee Osteoarthritis

Lead Sponsor:

Indiana University

Collaborating Sponsors:

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Conditions:

Osteoarthritis, Knee

Eligibility:

All Genders

60+ years

Phase:

PHASE2

Brief Summary

To understand the effects of leg strengthening exercise, we will study the effects of strength training of the legs in four groups of people: (1) osteoarthritis (OA) with knee pain; (2) OA without kne...

Detailed Description

Several studies have confirmed that weak leg muscles are associated with osteoarthritis (OA) of the knee. Studies of body composition in these people have also shown that, despite being weaker, people...

Eligibility Criteria

Inclusion Criteria:

  • Males and females 60 to 100 years of age

Exclusion Criteria:

  • Knee joint replacement surgery
  • Diabetes mellitus
  • Uncontrollable hypertension
  • Neuropathies of the lower extremity
  • Poor mental cognition (i.e., inability to follow instructions)

Key Trial Info

Start Date :

September 1 1977

Trial Type :

INTERVENTIONAL

End Date :

November 1 2006

Estimated Enrollment :

280 Patients enrolled

Trial Details

Trial ID

NCT00000406

Start Date

September 1 1977

End Date

November 1 2006

Last Update

April 30 2013

Active Locations (1)

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1

National Institute for Fitness and Sport

Indianapolis, Indiana, United States, 46202