Status:

COMPLETED

Ondansetron Treatment for Alcoholism

Lead Sponsor:

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

Conditions:

Alcoholism

Eligibility:

All Genders

25-60 years

Phase:

PHASE2

Brief Summary

The purpose of this study is to: a) evaluate the effectiveness of ondansetron (Zofran) in the treatment of alcohol dependent patients; b) investigate whether early versus late onset alcoholism predict...

Eligibility Criteria

Inclusion Criteria:

  • Meet criteria for alcohol dependence.
  • Subjects with early onset alcoholism must also have a diagnosis of antisocial personality disorder.
  • Understand the requirements of the study and be able to complete the questionnaires and rating scales.

Exclusion Criteria:

  • Current diagnosis of substance dependence or self-report of having used narcotics (opiates, cocaine, amphetamine-like substances, and hallucinogens) in the 30 day period prior to study.
  • Positive urine drug screen test for narcotics, barbiturates, or benzodiazepines.
  • Receiving current psychotropic medications.
  • Current history of other psychiatric disorders excluding nicotine dependence.
  • Hepatocellular disease.
  • Pregnant females.

Key Trial Info

Start Date :

Trial Type :

INTERVENTIONAL

End Date :

April 1 2000

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00000443

End Date

April 1 2000

Last Update

June 24 2005

Active Locations (1)

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1

Substance Abuse Research Center, University of Texas Health Science Center

Houston, Texas, United States, 77030