Inclusion Criteria:

• Meets criteria for alcohol dependence. Abstinent from alcohol for a period of at least 5 days.
• Able to read English and complete study evaluations.
• A stable residence and a telephone to ensure that subjects can be located during the study.

Exclusion Criteria:

• Meets criteria for dependence on another psychoactive substance besides alcohol or nicotine.
• Regular use of psychoactive drugs except antidepressants.
• Current use of disulfiram (Antabuse).
• Psychotic or otherwise severely psychiatrically disabled.
• Significant underlying medical conditions such as cerebral, renal, thyroid, or cardiac pathology.
• Abstinent longer than 30 days prior to admission to program.
• Hepatocellular disease or elevated bilirubin levels.
• Individuals with present history of opiate abuse or who require the use of opioid analgesics.
• Women who are pregnant, nursing, or not using a reliable method of birth control.
• Women who are significantly overweight or significantly underweight.