Status:
COMPLETED
Harvard Atherosclerosis Reversibility Project (HARP)
Lead Sponsor:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Cardiovascular Diseases
Coronary Disease
Eligibility:
All Genders
18-75 years
Phase:
PHASE2
Brief Summary
To determine by sequential coronary arteriography whether a lipid-lowering diet with and without lipid-lowering drugs could reverse coronary artery disease in normocholesterolemic patients. Also, to t...
Detailed Description
BACKGROUND: The prognosis of patients with coronary heart disease is closely related to the degree of coronary luminal obstruction. In population studies, the incidence and severity of coronary ather...
Eligibility Criteria
Men and women, normocholesterolemic, with 30 percent or greater narrowing of a coronary artery lumen as revealed by angiography. (Cholesterol-Lowering Agent Trial).
Men and women with angiographically-documented coronary heart disease (Fish Oil Tr
Key Trial Info
Start Date :
December 1 1986
Trial Type :
INTERVENTIONAL
End Date :
November 1 1992
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00000461
Start Date
December 1 1986
End Date
November 1 1992
Last Update
March 16 2016
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