Status:
COMPLETED
Treatment of Mild Hypertension Study (TOMHS)
Lead Sponsor:
University of Minnesota
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Cardiovascular Diseases
Heart Diseases
Eligibility:
All Genders
45-69 years
Phase:
PHASE2
Brief Summary
To compare the effects of nonpharmacologic therapy alone with those of one of five active drug regimens combined with non-pharmacologic therapy, for long- term management of patients with mild hyperte...
Detailed Description
BACKGROUND: Dietary sodium reduction has a mild effect on the reduction of hypertension. Weight loss, while achievable in the short-run with diet alone, may also have only mild effects on hypertensio...
Eligibility Criteria
Men and women, ages 45 to 69, with mild hypertension (diastolic blood pressure of 90-99 mm Hg at two of three visits for untreated individuals. Patients who received drug therapy must have had a DBP less than 95 mm Hg two to four weeks after drug.
Key Trial Info
Start Date :
August 1 1985
Trial Type :
INTERVENTIONAL
End Date :
May 1 1994
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00000522
Start Date
August 1 1985
End Date
May 1 1994
Last Update
February 25 2016
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