Status:

COMPLETED

Diuretics, Hypertension, and Arrhythmias Clinical Trial

Lead Sponsor:

University of California, San Francisco

Collaborating Sponsors:

National Heart, Lung, and Blood Institute (NHLBI)

Conditions:

Cardiovascular Diseases

Death, Sudden, Cardiac

Eligibility:

MALE

35-70 years

Phase:

PHASE3

Brief Summary

To determine whether hypertensive patients with ECG abnormalities and receiving hydrochlorothiazide diuretics were at increased risk of sudden death.

Detailed Description

BACKGROUND: The Multiple Risk Factor Intervention Trial (MRFIT) revealed an unexpected subgroup finding: an association between diuretic therapy (especially with hydrochlorothiazide) and an increased...

Eligibility Criteria

Men, ages 35 to 70, with ECG abnormalities, diastolic blood pressure less than 95 mm Hg at entry.

Subjects had been treated for at least six months by their own physicians with hydrochlorothiazide (HCT), HCT and potassium supplementation, triamteren

Key Trial Info

Start Date :

July 1 1986

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

Estimated Enrollment :

233 Patients enrolled

Trial Details

Trial ID

NCT00000525

Start Date

July 1 1986

Last Update

September 19 2013

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Diuretics, Hypertension, and Arrhythmias Clinical Trial | DecenTrialz