The effects of ibuprofen on the physiology and survival of patients with sepsis. The Ibuprofen in Sepsis Study Group.
G R Bernard, A P Wheeler, J A Russell...
https://pubmed.ncbi.nlm.nih.gov/9070471Completed
Led by Vanderbilt University · Updated on 2016-02-01
N/A
Participants Needed
N/A
Research Sites
N/A
Total Duration
V
Vanderbilt University
Lead Sponsor
N
National Heart, Lung, and Blood Institute (NHLBI)
Collaborating Sponsor
To determine the effects of ibuprofen on mortality, development and reversal of shock, and adult respiratory distress syndrome, and on Lung Parenchymal Injury Score in adult patients with serious infection.
CONDITIONS
Ibuprofen in Sepsis Study
You may qualify if you...
Men and women patients with known or suspected sites of serious infection if core temperature was 38.3 degrees Celsius, heart rate 90 in the absence of beta-blockers, respiratory rate 20 or minute ventilation 10 liters per minute. In addition, one o
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Site Locations not provided
Location information for this trial is currently unavailable.
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
N/A
Primary Purpose
TREATMENT
Number of Arms
0
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G R Bernard, A P Wheeler, J A Russell...
https://pubmed.ncbi.nlm.nih.gov/9070471