Completed
Phase 3
Age: 13Years +
All Genders
ID00000579
Acute Respiratory Distress Syndrome Clinical Network (ARDSNet)
Led by National Heart, Lung, and Blood Institute (NHLBI) ยท Updated on 2016-03-23
N/A
Participants Needed
21
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
The purposes of this study are to assess rapidly innovative treatment methods in patients with adult respiratory distress syndrome (ARDS) as well as those at risk of developing ARDS and to create a network of interactive Critical Care Treatment Groups (CCTGs) to establish and maintain the required infrastructure to perform multiple therapeutic trials that may involve investigational drugs, approved agents not currently used for treatment of ARDS, or treatments currently used but whose efficacy has not been well documented.
CONDITIONS
Official Title
Acute Respiratory Distress Syndrome Clinical Network (ARDSNet)
Who Can Participate
Age: 13Years +
All Genders
Eligibility Criteria
You may qualify if you...
Inclusion Criteria:
- Men and women
- 13 years of age or older
- ARDS or risk factors for ARDS (patients will be considered at risk if they are critically ill and have trauma, sepsis, shock, pneumonia, inhalation injury, drug overdose, pancreatitis, or hypertransfusion)
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Trial Site Locations
Total: 21 locations
1
University of California
San Francisco, California, United States, 94143
Status Unknown
2
University of Colorado Health Sciences Center
Denver, Colorado, United States, 80262
Status Unknown
3
University of Chicago
Chicago, Illinois, United States, 60637
Status Unknown
4
Louisiana State University
New Orleans, Louisiana, United States, 70112
Status Unknown
5
University of Maryland
Baltimore, Maryland, United States, 21201
Status Unknown
6
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
Status Unknown
7
Baystate Medical Center
Springfield, Massachusetts, United States, 01199
Status Unknown
8
University of Michigan
Ann Arbor, Michigan, United States, 48109
Status Unknown
9
Mayo Foundation
Rochester, Minnesota, United States, 55905
Status Unknown
10
Duke University
Durham, North Carolina, United States, 27708
Status Unknown
11
Wake Forest University
Winston-Salem, North Carolina, United States, 27157
Status Unknown
12
Cleveland Clinic Foundation
Cleveland, Ohio, United States, 44195
Status Unknown
13
University of Pennsylvania
Philadelphia, Pennsylvania, United States, 19104
Status Unknown
14
University of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15261
Status Unknown
15
Vanderbilt University
Nashville, Tennessee, United States, 37232
Status Unknown
16
Baylor College of Medicine
Houston, Texas, United States, 77030
Status Unknown
17
University of Texas
San Antonio, Texas, United States, 78229-3900
Status Unknown
18
Latter Day Saints Hospital
Salt Lake City, Utah, United States, 84143
Status Unknown
19
University of Virginia
Charlottesville, Virginia, United States, 22908
Status Unknown
20
University of Washington
Seattle, Washington, United States, 98105
Status Unknown
21
University of British Columbia
Vancouver, British Columbia, Canada, V5Z 1M9
Status Unknown
Loading map...
How is the study designed?
Study Type
INTERVENTIONAL
Masking
N/A
Allocation
N/A
Model
FACTORIAL
Primary Purpose
TREATMENT
Number of Arms
0
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here
Published Research Related To This Trial
Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome.
Acute Respiratory Distress Syndrome Network, Roy G Brower, Michael A Matthay...
https://pubmed.ncbi.nlm.nih.gov/10793162Mechanical ventilation in acute lung injury and acute respiratory distress syndrome.
R G Brower, H E Fessler
https://pubmed.ncbi.nlm.nih.gov/11019722Variability among institutional review boards' decisions within the context of a multicenter trial.
H Silverman, S C Hull, J Sugarman
https://pubmed.ncbi.nlm.nih.gov/11246299Efficacy of low tidal volume ventilation in patients with different clinical risk factors for acute lung injury and the acute respiratory distress syndrome.
M D Eisner, T Thompson, L D Hudson...
https://pubmed.ncbi.nlm.nih.gov/11463593Clinicians' approaches to mechanical ventilation in acute lung injury and ARDS.
B T Thompson, D Hayden, M A Matthay...
https://pubmed.ncbi.nlm.nih.gov/11713144Recovery rate and prognosis in older persons who develop acute lung injury and the acute respiratory distress syndrome.
E Wesley Ely, Arthur P Wheeler, B Taylor Thompson...
https://pubmed.ncbi.nlm.nih.gov/11777361Randomized, placebo-controlled trial of lisofylline for early treatment of acute lung injury and acute respiratory distress syndrome.
https://pubmed.ncbi.nlm.nih.gov/11902249Implementation of a low tidal volume ventilation protocol for patients with acute lung injury or acute respiratory distress syndrome.
R H Kallet, W Corral, H J Silverman...
https://pubmed.ncbi.nlm.nih.gov/11572755Statistical evaluation of ventilator-free days as an efficacy measure in clinical trials of treatments for acute respiratory distress syndrome.
David A Schoenfeld, Gordon R Bernard, ARDS Network
https://pubmed.ncbi.nlm.nih.gov/12163791