Inclusion Criteria

Patients may be eligible for this study if they:

• Are HIV-positive.
• Have a stable viral load of at least 1,500 copies/ml within 30 days of study entry.
• Are on stable aggressive anti-HIV therapy for at least 8 weeks before study entry and intend to remain on this therapy during the study.
• Agree to learn how to give themselves the GM-CSF shots.
• Agree to practice acceptable barrier methods of birth control (such as condoms) during the study and for at least 12 weeks after treatment ends.
• Are at least 18 years old.

Exclusion Criteria

Patients will not be eligible for this study if they:

• Have an infection or other illness within 14 days of study entry.
• Have certain types of hepatitis within 30 days of study entry.
• Have a fever or chronic diarrhea within 30 days of study entry.
• Have cancer (except for certain types of Kaposi's sarcoma).
• Have heart disease.
• Are allergic to GM-CSF.
• Have received certain medications.
• Are pregnant or breast-feeding.