Inclusion Criteria

Patients must have:

• Premenopausal status.
• Intact uterus and cervix.
• Documented HIV infection.
• Current enrollment in a multisite longitudinal study, Women's Interagency HIV Study (WIHS).

Required:

• Stable or no antiretroviral therapy within 1 month prior to study entry.

Exclusion Criteria

Concurrent Medication:

Excluded:

• Antifungal or antimicrobial medication in the vagina.

Prior Medication:

Excluded:

• Antimicrobial or antifungal medications during the 48 hours prior to study entry.
• Use of spermicide or douche in the 48 hours prior to entry.

Coital interaction during the 48 hours prior to study visit, as reported by subject and confirmed by a negative seminal fluid assay result.