Status:
COMPLETED
A Study to Learn More About MAC Disease and the Use of Anti-HIV Drugs in Patients With Advanced HIV Infection
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Conditions:
Mycobacterium Avium-intracellulare Infection
HIV Infections
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to determine if infection with Mycobacterium avium complex (MAC) occurs in other parts of the body before it is found in the blood. This study also evaluates the relations...
Detailed Description
The intent of this study is to define more precisely the natural history and immunopathogenesis of MAC disease in the HIV-infected population. It is suggested that MAC disease in AIDS patients results...
Eligibility Criteria
Inclusion Criteria
You may be eligible for this study if you:
- Are HIV-positive.
- Have a CD4 count under 50 cells/mm3 or between 100 and 250 cells/mm3 within 30 days of study entry.
- Have at least one symptom (e.g., fever, diarrhea, or weight loss) suggestive of MAC infection.
- Have MAC infection with 7 days or less of MAC treatment.
- Have an HIV blood level greater than 10,000 copies/ml within 30 days of study entry.
- Are 18 years of age or older.
Exclusion Criteria
You will not be eligible for this study if you:
- Have any active infection (except for MAC in Group 2 patients) or any cancer.
- Are unable to follow an acceptable anti-HIV drug regimen (Groups 2 and 3).
- Are pregnant or breast-feeding.
Key Trial Info
Start Date :
Trial Type :
INTERVENTIONAL
End Date :
August 1 2001
Estimated Enrollment :
85 Patients enrolled
Trial Details
Trial ID
NCT00000895
End Date
August 1 2001
Last Update
October 29 2021
Active Locations (26)
Enter a location and click search to find clinical trials sorted by distance.
1
Univ of Alabama at Birmingham
Birmingham, Alabama, United States, 35294
2
Univ of Southern California / LA County USC Med Ctr
Los Angeles, California, United States, 900331079
3
Univ of California / San Diego Treatment Ctr
San Diego, California, United States, 921036325
4
Stanford Univ Med Ctr
Stanford, California, United States, 943055107