Status:
COMPLETED
A Study to Evaluate the Impact of Stopping Treatment for the Prevention of Pneumonia in HIV-Positive Patients Receiving Anti-HIV Drugs Who Have Increased CD4 Cell Counts
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Conditions:
Pneumonia, Pneumocystis Carinii
HIV Infections
Eligibility:
All Genders
13+ years
Brief Summary
The purpose of this study is to see how often Pneumocystis carinii pneumonia (PCP) occurs in HIV-positive patients who have stopped taking medications that help prevent PCP. The risk of developing PC...
Detailed Description
The risk of developing PCP may be decreased with treatment-induced recovery of CD4 counts to \> 200 cells/mm3. Few data exist to confirm or negate the continued necessity of PCP prophylaxis for such p...
Eligibility Criteria
Inclusion Criteria
You may be eligible for this study if you:
- Are HIV-positive.
- Have had 1 CD4 cell count of less than 100 cells/mm3 and have never had PCP, or have had at least 2 CD4 cell counts over 200 cells/mm3 and have had PCP within 6 months prior to study entry.
- Have received PCP prevention medication within 3 months of study entry.
- Are at least 13 years old (need consent if under 18).
- Are taking anti-HIV (antiretroviral) medication at study entry.
Exclusion Criteria
You will not be eligible for this study if you:
- Have active PCP or symptoms of PCP within 2 weeks of study entry.
- Have a fever lasting more than 2 weeks.
- Have oral candidiasis (thrush).
Key Trial Info
Start Date :
Trial Type :
OBSERVATIONAL
End Date :
Estimated Enrollment :
250 Patients enrolled
Trial Details
Trial ID
NCT00000908
Last Update
June 24 2005
Active Locations (54)
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1
Univ of Alabama at Birmingham
Birmingham, Alabama, United States, 35294
2
Kaiser Foundation Hosp
Harbor City, California, United States, 90710
3
Kaiser Permanente LAMC
Los Angeles, California, United States, 90027
4
Univ of Southern California / LA County USC Med Ctr
Los Angeles, California, United States, 900331079