Status:
COMPLETED
Metabolism of Antituberculosis Drugs in HIV-Infected Persons With Tuberculosis
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Conditions:
HIV Infections
Tuberculosis
Eligibility:
All Genders
13+ years
Phase:
NA
Brief Summary
The purpose of this study is to determine if a relationship exists between the level of antituberculosis drugs (isoniazid, rifampin, ethambutol, and pyrazinamide) in the blood and the outcome of HIV-p...
Detailed Description
Patients receive up to 8 weeks of two or more anti-tuberculosis drugs, of which at least two are isoniazid, rifampin, pyrazinamide, or ethambutol. Blood specimens are collected at 2, 6, and 10 hours a...
Eligibility Criteria
Inclusion Criteria
You may be eligible for this study if you:
- Are HIV-positive and have tuberculosis.
- Are 13 years of age or older.
- Have written, informed consent of parent or guardian if you are under 18 years of age.
- Agree to practice abstinence or use barrier methods of birth control during the study.
Exclusion Criteria
You will not be eligible for this study if you:
- Have any other disorder or condition which might cause study treatment to be undesirable.
- Are pregnant.
Key Trial Info
Start Date :
Trial Type :
INTERVENTIONAL
End Date :
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT00000950
Last Update
March 2 2011
Active Locations (13)
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1
Univ of Southern California / LA County USC Med Ctr
Los Angeles, California, United States, 900331079
2
Harbor UCLA Med Ctr
Torrance, California, United States, 90502
3
University of Miami (Pediatric)
Miami, Florida, United States, 33136
4
Emory Univ
Atlanta, Georgia, United States, 30308