Inclusion Criteria

Concurrent Medication:

Allowed:

• Ongoing and/or maintenance therapy for opportunistic infection.
• Medications for nausea, vomiting, and diarrhea resulting from drug.

Patients must have AIDS related Kaposi's sarcoma.

• Patients may demonstrate positive blood cultures for Mycobacterium avium-complex or cytomegalovirus.

Exclusion Criteria

Co-existing Condition:

Patients with the following conditions will be excluded:

• Patients with active opportunistic infection.
• Patients with concurrent neoplasm other than squamous cell carcinoma of the skin or in situ carcinoma of the cervix.
• Patients with significant neurologic, cardiac, or liver disease.

Concurrent Medication:

Excluded:

• Antiretroviral agents.
• Immunomodulators.
• Corticosteroids.
• Experimental drugs.

The following patients will be excluded from the study:

• Patients with lymphadenopathy alone and/or visceral disease alone secondary to Kaposi's sarcoma.

Prior Medication:

Excluded:

• Cytotoxic chemotherapy.
• Excluded within 30 days of study entry:
• Antiretroviral agents.
• Biologic modifiers.
• Corticosteroids.

Prior Treatment:

Excluded:

• Total body electron beam therapy.
• Excluded within 30 days of study entry:
• Radiation therapy.