Inclusion Criteria

Concurrent Medication:

Allowed:

• Prophylactic pentamidine for Pneumocystis carinii.

Patients must have:

• HIV seropositivity.
• CD4 count > 50 and < 200 cells/mm3.
• No active opportunistic infections.

Exclusion Criteria

Co-existing Condition:

Patients with the following symptoms or conditions are excluded:

• Concurrent neoplasms other than basal cell carcinoma of the skin, in situ carcinoma of the cervix, or Kaposi's sarcoma.
• Significant cardiac disease or CNS lesions or other neurologic abnormalities.
• Score of > 0.5 on ACTG AIDS Dementia Complex staging.
• Major organ allograft.
• Intolerance to AZT at 500 mg/day.

Concurrent Medication:

Excluded:

• Antihypertensive medication other than diuretics.
• Chemotherapy, hormonal therapy, or other immunotherapy.
• Other investigational drugs, agents, or devices.
• Beta-blockers.
• Non-topical steroids.

Concurrent Treatment:

Excluded:

• Radiation therapy.

Prior Medication:

Excluded:

• Known anti-HIV medication (other than AZT) or known immunomodulators (e.g., systemic steroids, interferons, interleukins) or other chemotherapy within 30 days prior to study entry.

Prior Treatment:

Excluded:

• Transfusion within 4 weeks prior to study entry.
• Radiation within 30 days prior to study entry.

Active substance abuse.