Effect of lamivudine in HIV-infected persons with prior exposure to zidovudine/didanosine or zidovudine/zalcitabine.
M A Albrecht, M D Hughes, S H Liou...
https://pubmed.ncbi.nlm.nih.gov/11018853Completed
Phase 2
Age: 12Years +
All Genders
ID00001068
Influence of Risk Status for Disease Progression on the Response to Antiretroviral Interventions: A Follow-up Study to ACTG 175
Led by National Institute of Allergy and Infectious Diseases (NIAID) · Updated on 2021-11-04
210
Participants Needed
41
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
To determine the influence of virus load, CD4 count, biologic phenotype, and presence of symptomatic disease on the response of HIV-infected patients to a new therapeutic regimen. PER AMENDMENT 8/27/96: To extend the availability of currently assigned ACTG 303 treatment for 6 months.
CONDITIONS
Official Title
A Study of Disease Progression and Anti-HIV Treatments
Who Can Participate
Age: 12Years +
All Genders
Eligibility Criteria
You may qualify if you...
Inclusion Criteria
Patients must have:
- Prior participation on protocol ACTG 175.
PER AMENDMENT 8/27/96:
- Patients must be on study/on treatment at the time the protocol study treatment is extended.
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Trial Site Locations
Total: 41 locations
1
Alabama Therapeutics CRS
Birmingham, Alabama, United States, 35294
Status Unknown
2
USC CRS
Los Angeles, California, United States, 90033
Status Unknown
3
UCLA CARE Center CRS
Los Angeles, California, United States, 90095
Status Unknown
4
Stanford CRS
Palo Alto, California, United States, 94115
Status Unknown
5
Ucsd, Avrc Crs
San Diego, California, United States
Status Unknown
6
Ucsf Aids Crs
San Francisco, California, United States, 94110
Status Unknown
7
Santa Clara Valley Med. Ctr.
San Jose, California, United States, 95128
Status Unknown
8
San Mateo County AIDS Program
Stanford, California, United States, 94305
Status Unknown
9
Harbor-UCLA Med. Ctr. CRS
Torrance, California, United States, 90502
Status Unknown
10
University of Colorado Hospital CRS
Aurora, Colorado, United States
Status Unknown
11
Univ. of Miami AIDS CRS
Miami, Florida, United States, 33136
Status Unknown
12
Emory Univ. Hemophilia Program Office
Atlanta, Georgia, United States, 30365
Status Unknown
13
Northwestern University CRS
Chicago, Illinois, United States, 60611
Status Unknown
14
Cook County Hosp. CORE Ctr.
Chicago, Illinois, United States, 60612
Status Unknown
15
Rush Univ. Med. Ctr. ACTG CRS
Chicago, Illinois, United States, 60612
Status Unknown
16
Indiana Univ. School of Medicine, Infectious Disease Research Clinic
Indianapolis, Indiana, United States
Status Unknown
17
Tulane Hemophilia Treatment Ctr.
New Orleans, Louisiana, United States
Status Unknown
18
Johns Hopkins Adult AIDS CRS
Baltimore, Maryland, United States, 21287
Status Unknown
19
Massachusetts General Hospital ACTG CRS
Boston, Massachusetts, United States, 02114
Status Unknown
20
Bmc Actg Crs
Boston, Massachusetts, United States, 02118
Status Unknown
21
Beth Israel Deaconess - East Campus A0102 CRS
Boston, Massachusetts, United States
Status Unknown
22
Beth Israel Deaconess Med. Ctr., ACTG CRS
Boston, Massachusetts, United States
Status Unknown
23
University of Minnesota, ACTU
Minneapolis, Minnesota, United States, 55455
Status Unknown
24
St. Louis ConnectCare, Infectious Diseases Clinic
St Louis, Missouri, United States
Status Unknown
25
Washington U CRS
St Louis, Missouri, United States
Status Unknown
26
Univ. of Nebraska Med. Ctr., Durham Outpatient Ctr.
Omaha, Nebraska, United States, 68198
Status Unknown
27
SUNY - Buffalo, Erie County Medical Ctr.
Buffalo, New York, United States, 14215
Status Unknown
28
Beth Israel Med. Ctr. (Mt. Sinai)
New York, New York, United States, 10003
Status Unknown
29
NY Univ. HIV/AIDS CRS
New York, New York, United States, 10016
Status Unknown
30
Cornell University A2201
New York, New York, United States, 10021
Status Unknown
31
Univ. of Rochester ACTG CRS
Rochester, New York, United States, 14642
Status Unknown
32
Unc Aids Crs
Chapel Hill, North Carolina, United States, 27599
Status Unknown
33
Carolinas HealthCare System, Carolinas Med. Ctr.
Charlotte, North Carolina, United States, 28203
Status Unknown
34
Regional Center for Infectious Disease, Wendover Medical Center CRS
Greensboro, North Carolina, United States, 27401
Status Unknown
35
Univ. of Cincinnati CRS
Cincinnati, Ohio, United States, 45267
Status Unknown
36
Case CRS
Cleveland, Ohio, United States, 44106
Status Unknown
37
The Ohio State Univ. AIDS CRS
Columbus, Ohio, United States, 43210
Status Unknown
38
Hosp. of the Univ. of Pennsylvania CRS
Philadelphia, Pennsylvania, United States, 19104
Status Unknown
39
University of Washington AIDS CRS
Seattle, Washington, United States, 98122
Status Unknown
40
Puerto Rico-AIDS CRS
San Juan, Puerto Rico, 00936
Status Unknown
41
Mbeya Med. Research Program, Mbeya Referral Hosp. CRS
Mbeya, Tanzania
Status Unknown
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How is the study designed?
Study Type
INTERVENTIONAL
Masking
N/A
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
0
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