Status:
COMPLETED
Collection of Blood From Patients With Pancytopenia
Lead Sponsor:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Pancytopenia
Eligibility:
All Genders
18+ years
Brief Summary
Aplastic anemia is a condition in which the cells normally found in blood are greatly decreased. The normal levels of white blood cells, red blood cells, and platelets are much lower in patients with ...
Detailed Description
Patients with aplastic anemia, myelodysplasia, and other marrow failure syndromes have a variety of immunologic abnormalities including lymphocyte phenotypic and lymphokine production dysregulation. B...
Eligibility Criteria
- INCLUSION CRITERIA:
All patients with aplastic anemia or other bone marrow failure in which we would not expect to obtain 1 X 10(8) mononuclear cells from 100 mls of peripheral blood (i.e. an absolute lymphocyte count approximately less than 2000 per mm(3)).
Age greater than or equal to 18.
EXCLUSION CRITERIA:
Patients unable to comprehend the investigational nature of the procedure.
Patients unable to tolerate a temporary reduction of blood volume the equivalent of one unit of blood.
Key Trial Info
Start Date :
April 30 1986
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
August 17 2020
Estimated Enrollment :
38 Patients enrolled
Trial Details
Trial ID
NCT00001214
Start Date
April 30 1986
End Date
August 17 2020
Last Update
August 21 2020
Active Locations (1)
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1
National Institutes of Health Clinical Center, 9000 Rockville Pike
Bethesda, Maryland, United States, 20892