Actively Recruiting

Age: 18Years - 120Years
All Genders
ID00001276

Fasting Hypoglycemia Diagnosis and Treatment Study Researching Causes and Care for Low Blood Sugar

Led by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · Updated on 2026-05-12

1500

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying fasting hypoglycemia, a condition where blood sugar levels become abnormally low, caused by various factors including insulinomas and other pancreatic neuroendocrine tumors. This research aims to improve understanding of the causes and diagnosis of hypoglycemia, identify new biomarkers for insulinomas, and build a repository of clinical data and samples to support future studies. The study focuses on patients with documented low fasting blood glucose and biochemical evidence related to insulinomas. Participants will be admitted to the Clinical Center of the National Institutes of Health for evaluation and treatment based on standard care practices for their specific condition. During the study, patients will undergo tests including blood sugar monitoring and blood tests for insulin and other diagnostic markers. They will be required to fast for a set period before testing to accurately assess their blood glucose and insulin levels. Medical and surgical care will be provided as needed under close supervision. Throughout the study, patients will have treatment outcomes monitored every 1 to 3 months to evaluate their condition and response to therapy. The research team will collect clinical data and samples to better understand hypoglycemia caused by insulinomas. The duration of participation will vary according to individual treatment needs and monitoring schedules, with ongoing assessments to ensure patient safety and study goals are met.

CONDITIONS

Official Title

Diagnosing and Treating Low Blood Sugar Levels

Who Can Participate

Age: 18Years - 120Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male or female aged 18 years or older
  • Documented fasting blood glucose below 55 mg/dl
  • Biochemical evidence of insulinoma or other pancreatic neuroendocrine tumors
Not Eligible

You will not qualify if you...

  • Significant cardiac disease
  • Pregnant individuals
  • Medically unstable as assessed by the principal investigator

AI-Screening

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Trial Site Locations

Total: 1 location

1

National Institutes of Health Clinical Center

Bethesda, Maryland, United States, 20892

Actively Recruiting

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Research Team

C

Craig S Cochran, R.N.

R

Ranganath Muniyappa, M.D.

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Published Research Related To This Trial