Status:
COMPLETED
Treatment of Non-Tuberculous Mycobacterial Infections With Interferon Gamma
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Conditions:
Healthy
Mycobacterium Infections, Atypical
Eligibility:
All Genders
Phase:
PHASE2
Brief Summary
This is an open label study to determine the effects of the administration of Interferon-gamma on the clinical condition and immune function of patients with severe, treatment refractory non-tuberculo...
Detailed Description
This is an open label study to determine the effects of the administration of Interferon-gamma on the clinical condition and immune function of patients with severe, treatment refractory non-tuberculo...
Eligibility Criteria
Inclusion
- Demonstrated non-tuberculous mycobacterial infection, either disseminated or pulmonary.
- Received medical treatment for at least 3 months without improvement.
- Preserved renal, hepatic and hematologic function.
- Negative pregnancy urine and effective contraceptive.
- Age range greater than 5.
- No secondary immunodeficiency such as HIV or malignancy.
- Not currently receiving cytotoxic therapy within the past 3 months.
- Not pregnant or lactating.
- No seizure disorders.
- No known symptomatic cardiac disease.
Exclusion
Key Trial Info
Start Date :
August 1 1992
Trial Type :
INTERVENTIONAL
End Date :
November 1 2000
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00001318
Start Date
August 1 1992
End Date
November 1 2000
Last Update
March 4 2008
Active Locations (1)
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1
National Institute of Allergy and Infectious Diseases (NIAID)
Bethesda, Maryland, United States, 20892