Visualizing cortical activation during mental calculation with functional MRI.
L Rueckert, N Lange, A Partiot...
https://pubmed.ncbi.nlm.nih.gov/9345480Completed
Led by National Institute of Neurological Disorders and Stroke (NINDS) · Updated on 2008-03-04
830
Participants Needed
1
Research Sites
N/A
Total Duration
This study is divided into two parts. The first part of the study will use MRI technology to view the brain structure of patients with neurological disorders and normal volunteers. This portion of the study will attempt to detect specific areas of damage in the brains of patients with amnesia and dementia. It will also try to correlate the amount of brain damage with performance on tests used to measure memory. In the second part of the study, researchers plan to use MRI technology to study brain function of patients with neurological disorders and normal volunteers when they perform tasks. MRI signals during task performance will be used to record areas of the brain receiving more blood flow indicating increased activity. Researchers believe this study will help improve existing methods of evaluating patients with neurological disorders. In addition, this study may contribute information about areas of the brain involved in thought processing and motor and sensory function.
CONDITIONS
Magnetic Resonance Imaging for the Study of Patients With Neurological Disorders
You may qualify if you...
INCLUSION CRITERIA:
Subjects between the ages of 18 and 80.
EXCLUSION CRITERIA:
Patient must be able to give informed consent.
Patients with ferromagnetic objects in their bodies which might be adversely affected by MRI (surgical clips or metal fragments in or near brain, eye or blood vessels, cardiac or neurological pacemaker, cochlear impairments) will be excluded.
Pregnant or lactating women will be excluded. A pregnancy test will be administered to women of childbearing age.
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Total: 1 location
1
National Institute of Neurological Disorders and Stroke (NINDS)
Bethesda, Maryland, United States, 20892
Status Unknown
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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L Rueckert, N Lange, A Partiot...
https://pubmed.ncbi.nlm.nih.gov/9345480L Rueckert, I Appollonio, J Grafman...
https://pubmed.ncbi.nlm.nih.gov/8186531H S Levin, J Scheller, T Rickard...
https://pubmed.ncbi.nlm.nih.gov/8599565