Status:

COMPLETED

Effects of Season on Melatonin Secretion in Healthy Men and Women and Patients With Seasonal Affective Disorder

Lead Sponsor:

National Institute of Mental Health (NIMH)

Conditions:

Seasonal Affective Disorder

Eligibility:

All Genders

Brief Summary

As the seasons change during the course of the year, many animals show major changes in their behavior and physiology. Many of these changes are triggered by changes in the length of time each night t...

Detailed Description

Changes in the duration of nocturnal melatonin secretion that are induced by seasonal changes in the length of the night trigger many of the dramatic seasonal changes in behavior that occur in animals...

Eligibility Criteria

Normal volunteers must be free of psychiatric illnesses.

Patients must meet the criteria of Rosenthal et al. for the diagnosis of SAD, as determined by a DSM IV diagnostic interview, and must be free of other major psychiatric illnesses.

All subjects must be free of major medical illnesses and must not be taking medications on a regular basis.

Patients must not test positive for antibodies to the AIDS virus.

Key Trial Info

Start Date :

June 1 1995

Trial Type :

OBSERVATIONAL

End Date :

April 1 2000

Estimated Enrollment :

116 Patients enrolled

Trial Details

Trial ID

NCT00001485

Start Date

June 1 1995

End Date

April 1 2000

Last Update

March 4 2008

Active Locations (1)

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Page 1 of 1 (1 locations)

1

National Institute of Mental Health (NIMH)

Bethesda, Maryland, United States, 20892